2009 – 2013，伟德bv国际体育，博士(导师：张万斌 讲席教授)
2006 – 2009，华东理工大学，硕士(导师：赵敏 副教授)
2000 – 2004，浙江工业大学，学士

2019 – 至今，伟德bv国际体育，副研究员
2015 – 2019，伟德bv国际体育，助理研究员
2013 – 2015，伟德bv国际体育，博士后（合作导师：颜德岳 院士）
2004 – 2006，生物医药公司，研发员

1）催化反应的研究，如不对称氢化；新型配体的设计、合成及应用
2）药物和香料等合成工艺研究

主持国家自然科学基金青年及面上项目，上海市自然科学基金面上等科研项目，参与国家自然科学基金重点项目，国际合作项目、企业合作项目等。

(18)  Xinhong Cai, Yicong Luo, Jianzhong Chen,* and Wanbin Zhang*,(Hot paper)“Enantioselective Nickel-Catalyzed Hydrogenation of α-Alkylidene Succinimides Enabled by Weak Noncovalent Interactions”,  Angew. Chem. Int. Ed. 2025, 64, e202510401. DOI: 10.1002/anie.202510401. 

(17)  Bowen Li§, Jianzhong Chen§, and Wanbin Zhang*, “Efficient Preparation of ChiralHydroxylamines via Nickel-Catalyzed Asymmetric Hydrogenation of Oximes”, Org. Synth. 2025, 102, 236-250. DOI: 10.15227/orgsyn.102.0236. (§: co-first author). 

(16) Jianzhong Chen, Hanlin Wei, Ilya D. Gridnev, and Wanbin Zhang*,  “Weak Attractive Noncovalent Interactions in Metal-Catalyzed Asymmetric Hydrogenation”, Angew. Chem. Int. Ed. 2025, 64, e202425589. DOI: 10.1002/anie.202425589.

(15) Hanlin Wei, Yicong Luo, Jinhui Li, Jianzhong Chen,* Ilya D. Gridnev,* and Wanbin Zhang* ,“Enantioselective Synthesis of Chiral β2-Amino Phosphorus Derivatives via Nickel-Catalyzed Asymmetric Hydrogenation”,  J. Am. Chem. Soc. 2024, 147, 342–352. DOI: 10.1021/jacs.4c10623.

(14)  Jing Guan, Yicong Luo, Qiyuan Wang, Jianzhong Chen*, Wanbin Zhang*,“Copper-Catalyzed Asymmetric Hydrogenation of Unsymmetrical ortho-Br Substituted Benzophenones”, Angew. Chem. Int. Ed. 2024, 63, e202416313. DOI: 10.1002/anie.202416313.

(13)  Bowen Li,+ Zhiling Wang,+ Yicong Luo, Hanlin Wei, Jianzhong Chen,* Delong Liu, Wanbin Zhang*, "Nickel-Catalyzed Asymmetric Hydrogenation for the Preparation of α-Substituted Propionic Acids", Nat. Commun. 2024, 15 , 5482, DOI: doi.org/10.1038/s41467-024-49801-0.

(12) Jing Guan, Jianzhong Chen, Yicong Luo, Lisen Guo, and Wanbin Zhang*, "Copper-Catalyzed Chemoselective Asymmetric Hydrogenation of C=O Bonds of Exocyclic α,β-Unsaturated Pentanones".  Angew. Chem. Int. Ed. 2023, 62, e202306380.  DOI: 10.1002/anie.202510401.

(11) Hanlin Wei, Hao Chen, Jianzhong Chen*, Ilya. D. Gridnev* and Wanbin Zhang*, "Nickel-Catalyzed Asymmetric Hydrogenation of α-Substituted Vinylphosphonates and Diarylvinylphosphine Oxides" Angew. Chem. Int. Ed. 2023, 62, e202214990.  DOI: 10.1002/anie.202214990. 

(10) Bowen Li, Jianzhong Chen, Dan Liu, Ilya D. Gridnev, and Wanbin Zhang*, "Nickel-catalysed asymmetric hydrogenation of oximes", Nature Chem. 2022, 14, 920-927. DOI: 10.1038/s41557-022-00971-8.

(9) Dan Liu, Bowen Li, Jianzhong Chen, Ilya D. Gridnev, Deyue Yan and Wanbin Zhang*, “Ni-Catalyzed Asymmetric Hydrogenation of N-Aryl Imino Esters for the Efficient Synthesis of Chiral α-Aryl Glycines”, Nature Commun., 2020, 11, 5935. DOI: 10.1038/s41467-020-19807-5.

(8) Mo Wang, Lu Zhang, Xiaohong Huo, Zhenfeng Zhang, Qianjia Yuan, Panpan Li, Jianzhong Chen, Yashi Zou, Zhengxing Wu, and Wanbin Zhang*, (VIP)“Catalytic Asymmetric Synthesis of the Anti-COVID-19 Drug Remdesivir”, Angew. Chem. Int. Ed., 2020, 59, 20814-20819. DOI: 10.1002/anie.202011527.

(7) Yawen Hu, Jianzhong Chen, Bowen Li, Zhenfeng Zhang, Ilya D. Gridnev, and Wanbin Zhang*, "Nickel-Catalyzed Asymmetric Hydrogenation of 2-Amidoacrylates", Angew. Chem. Int. Ed., 2020, 59, 5371-5375. DOI:10.1002/anie.201916534.

(6) Jianzhong Chen, Feilong Li, Fang Wang, Yawen Hu, Zhenfeng Zhang, Min Zhao*, and Wanbin Zhang*, "Pd(OAc)2-Catalyzed Asymmetric Hydrogenation of α-Iminoesters", Org. Lett., 2019, 21, 9060-9065. DOI: 10.1021/acs.orglett.9b03452.

(5) Bowen Li, Jianzhong Chen, Zhenfeng Zhang, Ilya D. Gridnev, and Wanbin Zhang*, (VIP): "Ni-Catalyzed Asymmetric Hydrogenation of N-Sulfonyl Imines", Angew. Chem. Int. Ed., 2019, 58, 7329-7334. DOI:10.1002/anie.201902576.Cover Picture: DOI: 10.1002/anie.201905441. 

(4) Jianzhong Chen, Zhenfeng Zhang, Bowen Li, Feilong Li, Yulin Wang, Min Zhao, Ilya D. Gridnev, Tsuneo Imamoto and Wanbin Zhang*, "Pd(OAc)2-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines", Nature Commun., 2018, 9, 5000. DOI: 10.1038/s41467-018-07462-w.

(3) Jianzhong Chen, Zhenfeng Zhang, Delong Liu, and Wanbin Zhang*, “Palladium-Catalyzed Chemo- and Enantioselective C-O Bond Cleavage of a-Acyloxy Ketones via Hydrogenolysis”, Angew. Chem. Int. Ed., 2016, 55, 8444-8447.  doi.org/10.1002/anie.201603590.

(2) Jianzhong Chen, Delong Liu, Dongyang Fan, Yangang Liu, and Wanbin Zhang*, “Synthesis of Axially Chiral C10-BridgePHOS Oxides and Their Use as Organocatalysts in Enantioselective Allylations of Aldehydes”, Tetrahedron 2013, 69, 8161-8168. https://doi.org/10.1016/j.tet.2013.07.030.

(1) Jianzhong Chen, Delong Liu, Nicholas Butt, Chao Li, Dongyang Fan, Yangang Liu, and Wanbin Zhang*, “Palladium-Catalyzed Asymmetric Hydrogenation of a-Acyloxy-1-aryletheanones”, Angew. Chem. Int. Ed., 2013, 52, 11632-11636.  doi.org/10.1002/anie.201306231.

2017、2019年度横山亮次教师优秀论文奖，2023国家自然科学二等奖。

长期高酬招聘博士后（0091109001@sjtu.edu.cn）。